The registration of imported medical devices is vital in ensuring the quality, safety, and efficacy of healthcare products available in Nigeria. Nigeria relies on imported medical devices to provide essential medical care to its population. Registering imported medical devices in Nigeria involves regulatory authorities, manufacturers, and importers to ensure compliance with local laws and regulations. With the continuous advancement in medical technology and the increasing demand for medical devices, it is essential to have a robust regulatory framework in place. This article examines the importance of registration, the regulatory framework, and its benefits to Nigeria’s healthcare system.